The enhanced intestinal permeability of infant mice enables oral protein and macromolecular absorption without delivery technology
نویسندگان
چکیده
منابع مشابه
Surface-modified solid lipid nanoparticles for oral delivery of docetaxel: enhanced intestinal absorption and lymphatic uptake
Docetaxel is a potent anticancer drug, but development of an oral formulation has been hindered mainly due to its poor oral bioavailability. In this study, solid lipid nanoparticles (SLNs) surface-modified by Tween 80 or D-alpha-tocopheryl poly(ethylene glycol 1000) succinate (TPGS 1000) were prepared and evaluated in terms of their feasibility as oral delivery systems for docetaxel. Tween 80-e...
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Thylakoid membranes, derived from chloroplasts, have previously been shown to retard fat digestion and lower blood glucose levels after oral intake. The purpose of the present study was to investigate the effect of thylakoid membranes on the passage of methyl-glucose, dextran and ovalbumin over rat intestine in vitro using Ussing chambers. The results show that thylakoids retard the passage of ...
متن کاملSmall intestinal transit, absorption, and permeability in patients with AIDS with and without diarrhoea.
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ژورنال
عنوان ژورنال: International Journal of Pharmaceutics
سال: 2021
ISSN: 0378-5173
DOI: 10.1016/j.ijpharm.2020.120120